Midlife is a time when many men experience a decrease in energy and vitality. The body’s changes, like the loss of muscle or the rise in abdominal fat, can be a major burden. Mental losses, such as irritability and hopelessness, can also be a problem. This is something that men rarely talk about and attribute to the stress and demands of daily life. These complaints can sometimes be caused by something simple and easily fixable.

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Menopause in Men

Hot flashes, mood swings and a loss of drive are all common symptoms of menopause. A drop in the hormone levels of key sex hormones, can also lead to many complaints among men.

It is analogous to the menopause for women and is therefore also called the “menopause” in men. Also known as the “climacterium virile” in Latin, it is the “menopause”. Other terms include andropause, PEDAM (the abbreviation of “partial endocrine deficit of the elderly male” or PADAM (the abbreviation of “partial androgen deficiency for the aging female” or late-onset Hypogonadism).

All these terms refer to the same thing, hormonal changes in men, which occur with age and a decrease in testosterone. Menopause does not happen as abruptly in men, unlike in women. It happens much slower, almost insidiously.

How many men are affected by Testosterone Deficiency?

Not all older men are affected by a testosterone deficiency. The EAU guideline Male Hypogonadism states that only ten percent of men aged 40-79 years are affected by a testosterone deficiency. Only about six percent of these men have clear symptoms.

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What is the Role of Testosterone in Men?

Testosterone, a sex hormone, is the most important hormone for men. Because testosterone is responsible to the formation of male sex organs, it ensures a typical male physique, with an increased musculature and deep voice. It also promotes body hair growth, beard growth, and muscle mass. The body also uses testosterone to control sexual desire and fertility, as well as a variety of other vital processes.

Although testosterone is also produced in the adrenal glands by women, it is much less. The testosterone production in men is primarily in the Leydig’s interstitial cells of the testis. It also occurs in a smaller amount in the adrenal glands. The hypothalamus, pituitary and thyroid glands control it. These brain areas secrete so-called gonadotropin-releasing hormones, especially at night and early in the morning, which indirectly trigger testosterone production.

Causes

An underactivity in the testes can cause testosterone deficiency. There are many reasons for this. Reduced testosterone production can be caused by rare genetic defects such as Klinefelter Syndrome, a testicular cancer, or congenital developmental disorders such as Kallmann Syndrome.

However, acquired diseases such as severe inflammation or varicose veins can also permanently affect testosterone production. Most cases of testosterone deficiency in men are due to increasing age. This is called age-related hypogonadism.

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How does Testosterone Deficiency develop?

However, some men experience very distinct impairments due to the drop in hormones. As the European Association of Urology (EAU), emphasizes in their current guidelines, this is true even more so if the men affected are more overweight and older. Many concomitant diseases are more common in older men. These include insulin resistance, type 2 diabetic, obesity, lipid metabolism disorders, cardiovascular disease, and high blood pressure. The metabolic syndrome and certain medications can cause testosterone levels to fall more quickly. This can cause a variety of problems for those who are affected. It can also have noticeable effects on their mental and physical health as well as their sexuality.

Signs

These are some of the signs that can indicate a testosterone deficit in men:

  • A decreased desire to sex
  • Erectile dysfunction
  • Reduced muscle mass and strength loss
  • Abdominal fat increases
  • Reduced body hair
  • Listlessness, fatigue, and tiredness despite adequate sleep
  • Depression can swing from moody to depressing
  • It is difficult to fall asleep and stay asleep
  • Hot flashes
  • Reduced bone density (osteoporosis).
  • Metabolic syndrome

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